Interview with Dr. Yael Joffe PhD

Founder and Chief Science Officer 3X4 Genetics

I was studying architecture when my gran died from cancer. It was all so quick and no doctor could give me answers to why cancer. What could we do to prevent it, and how could we have treated it better? No answers at all! So I left architecture to become a dietitian, hoping to find answers. This was many decades ago, and I was disappointed and frustrated not to find any of the answers I was looking for. After becoming a dietitian I was working in London, when I was lucky enough to meet Dr Rosalynn Gill, a geneticist and a visionary who believed that the future of health and medicine was nutrigenomics, the scientific field that looks at the relationship between genetics and nutrition. I was hooked, and joined her start-up, the first company to build a nutrigenomics test for the market, as early as 2000. I knew so little about genetics, but I would learn. A few years later I went back to university to get my PhD in the genetics of obesity. I have been working in this field for 25 years, and I finally feel that I have found the answers I was looking for.

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The Art Of Saying No starts with Yes

As we navigate the phases of discovering what we truly want and who we want to become, our lives often feel like a constant game of tug-of-war.  

When I first started working in the Hamptons for Rachel Uchitel in 2007 at 22, I decided to become a "Yes man." I quickly realized that many of the wealthy people around me had endless demands—ice coffees, bagels, dry cleaning pickups, and someone to work out or hit tennis balls with. I also noticed their fancy cars and figured I could convince them to let me drive them while I ran these errands. That’s when my love for cars started to grow.

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Business & Markets Update

Market volatility feels like it's here to stay in the near-term, with trade war developments dominating throughout last week and no obvious or imminent end in sight there.  Even when we do get clarity on tariffs, fully understanding the longer term impact on both companies & us (the consumer) will take months, if not years. Trump headlines (and again, policy implications broadly), along with earnings and economic data will be the most obvious 3 points of focus for market participants for the time being. 

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Creatine: A Powerful Supplement for Enhanced Performance and Recovery

Creatine is one of the most researched and widely used supplements in the fitness community, known for its ability to boost strength, increase muscle mass, and improve high-intensity exercise performance. Whether you're an athlete, a regular gym-goer, or someone looking to enhance your workouts, adding creatine to your supplement regimen could be a game-changer. In this article, we’ll explore what creatine is, how it works, and why it can be a beneficial addition to your supplement stack.

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Interview with Megan Dolce

Co-Founder and Head Executive Coach of RIPE

Ripe exists to cut through the noise. In a world full of surface-level empowerment buzzwords, Ripe is about real ownership—owning your power, your potential, and the impact you’re here to make. We don’t just talk about confidence; we build it. We don’t just inspire women; we equip them. Ripe challenges the narrative that women need to ‘fit in’ to succeed in business. Instead, we focus on creating environments where they can expand, lead, and thrive on their own terms. It’s not about checking boxes; it’s about rewriting the whole damn playbook.

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Be Obsessed With Improvement 

Inspired by Eric Thomas, I’ve made it my mission to approach every day with the mindset of constant improvement. It may sound cliché or even a bit "woo-woo," but the truth is, this mindset simply works.

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Business & Markets Update

Woah: That was some month to kick off 2025… felt more like a quarter.  Story of last week, if we had to choose one?  Has to be AI.  A week ago today, the market sold off pretty aggressively on fears around a Chinese AI app called DeepSeek, which performs foundational AI models similar to OpenAI in the US, for a fraction of the cost.  Nvidia (basically the proxy for all things AI in the US stock market) was down close to 17%, or $465 BILLION of its market capitalization, on Monday…the largest such wipe out in market history.

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The Secret to Brian's Recent Fitness Transformation: Less is More

Brian is the epitome of high performance, but his recent fitness transformation is a testament to an often-overlooked principle: less is more when intensity is the priority. While most athletes and fitness enthusiasts are led to believe that more volume equates to more progress, Brian has flipped the script—proving that cutting back on total workload while increasing intensity leads to greater muscle growth, improved recovery, and enhanced performance.

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Interview with Peter Nelson

Founder of Sisu Sauna, Husband, Father of 2 , 28x Ultra Runner

No one tells you when you’re getting your initial idea off the ground the potential impact it may make on customers, friends, family, internal team members, and even the impact on people philanthropically.  One of the most rewarding parts has been the process of giving to those in need through our ability to run a profitable business.

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Being Your Authentic Self Always Wins

Staying true to your authentic self will always lead to success, even when fear creeps in. This past weekend, I hosted my very first all- Women’s High Performance experience, and I won’t lie—there were nerves. For the last five years, my brand has followed a specific path, and stepping into new territory felt like a leap. But it was time to push boundaries and elevate what we’ve built. High Performance Experiences was ready to add a new layer to an already thriving business, one that felt uniquely for women.

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Business & Markets Update

First things first- what a heck of a weekend for HPLT, with a hugely successful first all-women’s summit down in Miami.  GREAT WORK Brian / Melissa & team, and JOB WELL DONE to the 30+ women who attended and invested in their own self-growth and improvement journey, taking time out of their busy personal & family lives.  

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The Importance of Fiber: Why It's Crucial for Your Health

When we think about healthy eating, we often focus on proteins, healthy fats, or the latest trendy superfoods. But one nutrient that doesn’t always get the attention it deserves is fiber. Though it may seem simple, fiber is a powerhouse for your body. It supports everything from digestion to heart health, weight management, and even reducing the risk of chronic diseases. Simply put, fiber is essential to a healthy lifestyle. Let’s explore why you should make fiber a priority in your diet.

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Be Back Next Week!

Have a great week!

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Time Is Our Most Valuable Resource

The sooner we realize that time is finite, the sooner we can begin to live a life of true fulfillment. This past weekend, I attended the funeral of a 12-year-old boy who lost his battle with cancer. It was an incredibly difficult service, especially since I’ve known the family my entire life. As I sat there, my heart went out to them, and I couldn’t help but reflect on the unimaginable grief they must be feeling. As I left the funeral home, I couldn’t shake the thought that the only thing that truly matters in life is the time we have left with the people we love. Time is our most precious resource, and if you speak to anyone older than you, they’ll often express the same regret: a wish to have more time, to turn back the clock, to relive moments they can never get back.

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Business & Markets Update

Happy MLK Day / Happy Inauguration Day … Hope everyone enjoys their Monday and you’re able to charge up for the week ahead!! Let’s jump into it, plenty to get to.

It was a big week of ‘data points’ last week… lots of data.  Wednesday’s December inflation report (CPI) felt like by far the most important economic data point of the year so far.  Core CPI came in light vs expectations, which helped ease some inflationary fears, and stocks were off to the races, up up & away.  This helped move treasury yields lower, after a multi-week run higher.  The yield on 10yr treasuries traded from 4.80% to 4.60%, a significant 5-day move. 

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Why Meal Timing is Overrated

In the world of fitness, nutrition trends and advice come and go, but one concept that’s persisted for years is meal timing, or what’s often referred to as nutrient timing. The idea is that when you consume certain nutrients—particularly protein and carbohydrates—can have a significant impact on your performance, muscle growth, fat loss, and overall health.

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Interview with Brian Mazza

Founder of HPLT

After spending many years in the hospitality industry, I found myself feeling unfulfilled. I longed to reconnect with the energy and passion of my D1 soccer days, so I decided to merge my love for events, personal connections, and fitness. My goal was to create a space that combined all of these elements to foster a sustainable community. The vision for HPLT has always been to begin with summits, then expand into investments, a performance club, and a marketing company.

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Adversity Is Blind & Community Is Everything

Adversity is blind, personal, and always arrives without warning. It can strike suddenly, knocking us down and forcing us to rebuild our lives—much like we had to rebuild our home after an unexpected fire.

In those moments, we realize how deeply we depend on our community. Unfortunately, it often takes hitting rock bottom or facing catastrophe for us to truly understand how fragile life is. This past week, the world saw the devastation caused by the massive wildfires sweeping through California, destroying entire neighborhoods. I never thought it could happen to me or my family—until it did.

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Business & Markets Update

We.. are.. BACK!  After a slower last couple weeks of ‘24 during Christmas and New Years (HNY everyone!!), 2025 is off & running and there is no shortage of news flow or market volatility to kick things off. 

This past week was a 4-day trading week with equities closed on Thursday for our 39th President Jimmy Carter's Funeral, a long-standing tradition known as a ‘National Day of Mourning’.  Stocks were lower on the week, with the S&P posting a -2% move and the tech-heavy Nasdaq -2.34%.

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Rethinking Fitness: How Much Exercise Do You Really Need?

There’s a widespread belief that getting in great shape requires endless hours in the gym and working out every single day. However, this couldn’t be further from the truth. In reality, you can achieve your fitness goals with fewer, smarter workouts by focusing on key principles like intensity, recovery, and nutrition. Let’s break down why less can be more when it comes to building a sustainable fitness routine.

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